Researchers used a novel phosphate-activation reagent, 2-MeImIm-Cl, in an improved coupling reaction to increase the yield of ADP- or ATP-containing molecules. Unlike traditional reactions, the ...

Key nuclear processes in eukaryotes, including DNA replication, repair, and gene regulation, require extensive chromatin remodeling catalyzed by energy-consuming enzymes. It remains unclear how the ...

A straightforward and reproducible synthesis pathway for a diverse range of ATP- and ADP-coupled biomolecules has been developed by modifying an established reagent. Researchers at the Institute for ...

A simple two-carbon compound may have been a crucial player in the evolution of metabolism before the advent of cells, according to a new study. The finding potentially sheds light on the earliest ...