A research team led by investigators at McMaster University has identified an axonal guidance signaling pathway that cancer cells use to infiltrate the brain. The combined results of preclinical in ...

Neurotrophin signalling orchestrates a myriad of cellular events essential for the development, survival, and functional maintenance of sympathetic neurons. Neurotrophins such as nerve growth factor ...

A new pathway that is used by cancer cells to infiltrate the brain has been discovered by a team of Canadian and American research groups led by the Singh Lab at McMaster University. The research also ...

Within the human brain, movement is coordinated by a brain region called the striatum, which sends instructions to motor neurons in the brain. Those instructions are conveyed by two pathways, one that ...

A new study definitively reveals the existence of a system that had been theorized to clear metabolic wastes in the human brain. The study uses imaging in neurosurgery patients to show how brain's ...

The human brain builds mental representations of the world based on the signals and information detected via the human senses. While we perceive simultaneously occurring sensory stimuli as being ...

Medical University of South Carolina scientists report in Neuron that they have uncovered a way to restore an opioid-weakened brain pathway in a preclinical model. With funding from the National ...

Ischemic stroke is a major cause of death and disability, caused by a sudden loss of oxygen supply to the brain due to blocked blood vessels. Recanalization treatments such as intravenous thrombolysis ...

We describe an unusual case of a woman in her 30s who had recently undergone Roux-en-Y gastric bypass and presented to the emergency department with a 6-week history of intractable nausea and vomiting ...

Spinal cord injuries caused by external trauma, such as traffic accidents or falls, often lead to the permanent loss of motor and sensory functions. This is because the spinal cord—the central pathway ...