Proceedings of the National Academy of Sciences of the United States of America PNAS is the world's most-cited multidisciplinary scientific serial. It publishes high-impact research reports, ...

Haemoglobin is a paradigm for exploring allosteric regulation, wherein ligand binding at one site induces conformational changes that affect functional activity at a distant site. These structural ...

Artificial oxygen carriers and haemoglobin‐based therapies represent a rapidly evolving field that seeks to overcome the limitations of conventional blood transfusions. These therapies aim to ...

ARLINGTON, Va.– Red-blooded genealogists take note: The discovery in microbes of two oxygen-packing proteins, the earliest known ancestors to hemoglobin, brings scientists closer to identifying the ...

This is a preview. Log in through your library . Abstract The contribution of the porphyrin skeleton to the potential energy surface of metalloporphyrins is calculated by the semiempirical method of ...

Webbed feet, flipper-like wings and unique feathers all helped penguins adapt to life underwater. But by resurrecting two ancient versions of hemoglobin, a research team has shown that the evolution ...