Figure 1: CRISPR–Cas systems identified in uncultivated organisms. Figure 2: ARMAN-1 CRISPR array diversity and identification of the ARMAN-1 Cas9 PAM sequence. Figure 3: CRISPR–CasX is a dual-guided ...

The emergence of advanced genome editing technologies has revolutionized research in life sciences, offering an unprecedented ...

Researchers have found an unprecedented defense mechanism by which bacteria defend themselves against invading viruses. When the bacterial immune system gets overwhelmed, the CRISPR-Cas system ...

Precise tumor diagnosis and treatment require the support of abundant molecular information. However, conventional molecular diagnostic technologies gradually fail to satisfy the demands of clinical ...

Scientists led by a team at Stanford University have developed a compact, efficient CRISPR-Cas system, called CasMINI, which is about half the size of existing CRISPR-Cas systems, and which could have ...

A compact and efficient CRISPR-Cas system, named CasMINI, could be broadly useful for cell-engineering and gene-therapy applications because it is easier to deliver into cells. The findings appear in ...