In a groundbreaking advancement for cancer treatment, a research team led by Professor Xiang David Li from the Department of Chemistry at The University of Hong Kong (HKU) has made significant strides ...

纵观整项研究，我们不仅看到了FOCAS这一强大工具的威力，更看到了它所揭示的生物学复杂性。过去针对m6A的抗癌策略往往类似于“地毯式轰炸”（如全局抑制METTL3或FTO），虽然有效，但伴随着破坏管家功能的风险。

Researchers developed LS-170, an inhibitor of the ATAC complex, which suppressed oncogene expression and reduced tumor growth ...

Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer and begins in the cells lining the ...

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

A new randomized study finds that a lab test that reads tumor genes can identify which patients with recurrent prostate cancer will benefit from adding hormone therapy to radiation after surgery - the ...

The following filter criteria for genes differentially expressed were used: PDAC versus normal pancreas (bulk tissue), PDAC versus normal pancreas (microdissected normal ductal cells), and PDAC versus ...

Gene that drops early in pancreatic tumors linked to shorter survival at stage II. Findings could guide future treatment ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.