Druggable phosphatases in cancer and immune cells, with examples of their corresponding drugs. Structures of allosteric inhibitors targeting PP2A, PRL3, DUSP1/6, and SHP2 in cancer cells (left).

A research team from the Department of Pathology, School of Clinical Medicine, LKS Faculty of Medicine of the University of Hong Kong (HKUMed), in collaboration with the HKU State Key Laboratory of ...

A research team affiliated with UNIST has made a significant discovery explaining why liver cancers associated with obesity and metabolic disorders tend to be more aggressive and less responsive to ...

MINNEAPOLIS/ST. PAUL (07/10/2025) — A University of Minnesota Medical School-led research team discovered that a cancer signaling pathway has previously unrecognized roles in retina and brain blood ...

A study by the Mildred Scheel Early Career Center group led by Dr. Mohamed Elgendy at the TUD Faculty of Medicine provides fundamental insights into cancer biology. Published in the renowned journal ...

Colorectal tumors that underwent somatic next-generation sequencing (NGS) for 154-168 genes in an in-house laboratory between 2015 and 2022 were retrospectively identified. Microsatellite instability ...

Abstract Endotrophin (ETP) is a cleavage fragment of collagen VI α3 (COL6A3) that functions as a potent fibrotic and pro-tumorigenic factor. ETP is a ...

HKUMed reveals that Resmetirom, a drug for treating metabolic dysfunction-associated fatty liver disease (MAFLD), has the ...

JCO Precision Oncology Conversations features discussions with leading authors of JCO Precision Oncology articles, hosted by Dr. Abdul Rafeh Naqash. Join our experts in engaging conversations as they ...

Ovarian cancer is considered the deadliest cancer affecting the female reproductive system. One of the main reasons it is so dangerous is that it is usually discovered very late. In many patients, ...