Thyroid development represents a complex orchestration of cellular migration, differentiation and folliculogenesis, all of which are tightly regulated by an interplay of signalling pathways and ...

Understanding how cells differentiate during early embryonic development is crucial for advancing regenerative medicine and developmental biology. Pluripotent stem cells (PSCs) have been invaluable ...

Over half of our genomes consists of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life. Once dismissed as the "dark side" of the ...

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery. The process of how a humble single cell becomes an organism fascinates scientists across ...

Researchers have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos. When an embryo is first formed after fertilization, each cell has the ...

Scientists at the University of California, Santa Cruz (UCSC), used CRISPR to engineer cellular models of embryos that mimic what happens in the first few days after reproductive cells meet. These ...

University of Cambridge scientists have used human stem cells to create three-dimensional embryo-like structures that replicate certain aspects of very early human development - including the ...

A large genetic screen has revealed how stem cells transform into brain cells, exposing hundreds of genes that make this process possible. Among the discoveries is PEDS1, a gene now linked to a ...

Subscribe to our newsletter for the latest sci-tech news updates. When planning a trip, it's rare that you don't have a choice of route. One may be more direct, another more scenic; but regardless of ...

University of Cambridge scientists have used human stem cells to create three-dimensional embryo-like structures that replicate certain aspects of very early human development—including the production ...

Although embryonic stem cells (ESCs) have been successfully derived from mice and rats, efforts to establish chimeric and germline-competent ESC lines in species beyond rodents have been unsuccessful.