本研究揭示了感觉神经肽CGRP（降钙素基因相关肽）通过FAK–AKT–VEGF信号通路促进骨血管生成，并诱导骨血管内皮细胞分泌ANGPTL4（血管生成素样蛋白4），进而驱动骨髓间充质干细胞（BMSC）的成骨分化、抑制成脂分化，最终加速骨缺损修复。该发现为骨质疏松及 ...

The first three calcitonin gene-related peptide (CGRP) inhibitors approved for prevention of migraine displayed a reassuring safety profile in real-world clinical practice during the first 6 months ...

In this randomized controlled trial involving pediatric patients, fremanezumab led to greater reductions in the number of migraine days per month versus placebo, consistent with previous trials in ...

Most patients with migraine are women, and this observation is reflected in clinical studies. A pharmacologist and a neurologist from the United States argue that the efficacy of calcitonin ...

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