Little is currently known about the molecular determinants of energy barriers along enzyme catalytic pathways. Kern and co-workers have studied this question in adenylate kinase (Adk) and now reveal ...

Many enzymes require cofactors such as nicotinamide adenosine dinucleotide (NAD +) or nicotinamide adenosine dinucleotide phosphate (NADP +) to shuttle electrons ...

Under certain conditions, some algae are able to produce hydrogen -- a much sought-after green energy source. Its production takes place in the unique catalytic center of the unicellular algae and is ...

A peptide bridge is designed to construct a fusion enzyme with electrostatic cofactor channeling, reducing NADPH input by two orders of magnitude or decreasing reaction time threefold with the same ...