The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic locations, most notably regulatory regions such as promoters and enhancers.

A Targeted Methylation–Based Multicancer Early Detection Blood Test Preferentially Detects High-Grade Prostate Cancer While Minimizing Overdiagnosis of Indolent Disease Enzymatic conversion–mediated ...

By cleverly combining new techniques for analysing DNA at the level of individual molecules, we can achieve real breakthroughs in research into ...

DNA analysis is a crucial tool for identifying harmful pathogens, such as bacteria, viruses, or fungi, that cause infections.

Hospital for Sick Children in Toronto researchers are reporting that targeted RNA sequencing can detect clinically actionable alterations in 87% of tumors and provide decisive findings where DNA-seq ...

Objectives Understanding the molecular changes in the preclinical synovium is crucial for identifying factors that drive ...