Embryonic development is a meticulously orchestrated process in which spatial and temporal cues guide cell fate determination and tissue patterning. Central to this process is morphogen signalling – a ...

Researchers have identified Nr1h2, a critical transcription factor essential for early embryo development. Their findings enhance our understanding of gene regulation during blastoid formation and ...

Embryonic development is a finely orchestrated process in which a single cell differentiates into the myriad specialised tissues that comprise a fully formed organism. Central to this process are ...

Human cells decode dynamics Wnt signals using an anti-resonant filter that suppresses intermediate-frequency inputs and is ...

Over half of our genomes consists of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life. Once dismissed as the "dark side" of the ...

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery. The process of how a humble single cell becomes an organism fascinates scientists across ...

Scientists at the University of California, Santa Cruz (UCSC), used CRISPR to engineer cellular models of embryos that mimic what happens in the first few days after reproductive cells meet. These ...

Researchers have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four weeks after fertilization. This is ...

The team observed the emergence of the three-dimensional embryo-like structures under a microscope in the lab. These started producing blood (seen here in red) after around two weeks of development - ...

University of Cambridge scientists have used human stem cells to create three-dimensional embryo-like structures that replicate certain aspects of very early human development - including the ...

University of Cambridge scientists have used human stem cells to create three-dimensional embryo-like structures that replicate certain aspects of very early human development—including the production ...

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...