Scientists uncover a pivotal enzyme, XccOpgD, and its critical role in synthesizing C G16, a key compound used by Xanthomonas pathogens to enhance their virulence against plants. This breakthrough ...
Sugars known as glycans form dense envelopes around cells. But they’re often ignored in biological investigations because, unlike DNA, proteins and other cellular components, tools to study them are ...
Using a series of more than 1,000 X-ray snapshots of the shapeshifting of enzymes in action, researchers at Stanford University have illuminated one of the great mysteries of life – how enzymes are ...
The tool centers on a pig enzyme called ST3Gal1, and how scientists retrained it to bind to glycans instead of building them. This new glycan-binding enzyme, which scientists named sCore2, could help ...
Researchers have found a small molecule enzyme inhibitor capable of manipulating an immune process that plays an important role in cancers and autoimmune diseases. Researchers at the University of ...
University of Delaware biochemist Jeff Mugridge is trying to figure out how so-called mRNA eraser enzymes work in our cells, why those erasers can sometimes misbehave and lead to cancer, and how ...
Scientists have long struggled to target proteins that lack defined structure and are involved in cancer, neurodegenerative disorders like Parkinson's disease, and other serious illnesses. Now, a new ...
An enzyme called MARK2 has been identified as a key stress-response switch in cells in a study by researchers at Johns Hopkins Bloomberg School of Public Health. Overactivation of this type of stress ...