A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood. Researchers said the AI tool, ...

One of these enzymes from white blood cells, known as MMP12, does not remain outside of cells while it fights infections, but rather it can travel all the way to the center of cells. Understanding how ...

The protein community is awash in data. As of October, the UniProt database of protein sequences had more than 44 million entries. UniProt serves as a clearinghouse for sequences. Researchers who ...

Professor Nicolas Doucet and his team at Institut national de la recherche scientifique (INRS) made a major breakthrough earlier this year in the field of evolutionary conservation of molecular ...

Figure 1: The synthetic recursive +1 pathway. To further enrich the set for GEOs likely to function on C8, we docked a modelled reaction intermediate of the C8 substrate within the predicted active ...

While E. coli is one of the most studied organisms, the function of 30% of proteins that make up E. coli has not yet been clearly revealed. For this, an artificial intelligence was used to discover ...

Reporting in Science, researchers at UC Santa Barbara, UCSF and the University of Pittsburgh have developed a new workflow for designing enzymes from scratch, paving the way toward more efficient, ...

Engineered enzymes are poised to have transformative impacts across applications in energy, materials, biotechnology, and medicine. Recently, machine learning has emerged as a useful tool for enzyme ...