The sarcoplasmic reticulum (SR) is a specialised organelle in skeletal muscle fibres that plays a pivotal role in regulating calcium dynamics crucial for muscle contraction and relaxation. Acting as ...

Numerous motor and structural proteins compose a highly ordered structure known as the sarcomere, the basic unit of muscle contraction in heart and skeletal muscles. Sarcomeric myosin heavy chain ...

A supplement of ketones may be the magic bullet that allows patients using weight-loss drugs to avoid the potentially adverse side-effect of a shrinking heart and skeletal muscle, according to a ...

Abnormalities in intracellular calcium release and reuptake are responsible for decreased contractility in heart failure (HF). We have previously shown that cardiac ryanodine receptors (RyRs) are ...

Scientists improve on 3D bioprinting research by investigating the effects of neural cell integration into bioprinted muscle constructs to accelerate functional muscle regeneration. Wake Forest ...

From arthritis and heart failure to diabetes and menopause, many conditions are associated with muscle weakness and increased fat deposits. Now a multidisciplinary team of researchers at the ...

Skeletal muscle stem cells in hibernating Syrian hamsters preserve their ability to function by suppressing their activation ...

Proteins are essential for body growth and muscle building. However, protein metabolism varies depending on the body’s internal biological clock. Therefore, it is important to know how distribution of ...

Muscle twitches fall into two main types. There’s myoclonus, where a whole muscle or group of muscles twitch or spasm. Then ...