New research from Oregon Health & Science University for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications ...

A holistic inquiry into how toxic tau impacts synapses provides a new take on the processes that lead to neuronal dysfunction ...

New research from Oregon Health & Science University for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications ...

Researchers are uncovering how disrupted glutamatergic synapses drive diverse forms of intellectual disability, revealing new paths toward targeted treatments.

A research team led by Dr. Àlex Bayés, Head of the Molecular Physiology of the Synapse Group at the Institut de Recerca Sant Pau (IR Sant Pau), has achieved what for decades had been an elusive goal: ...

Family with sequence similarity 19 member A5 (FAM19A5) is a secretory protein highly expressed in the brain that regulates synapse dynamics through its interaction with leucine-rich repeat-containing ...

Clinical portfolio, informed by deep and novel synapse biology and pharmacology insights, aims to strengthen neural connections through event-driven pharmacology Lead candidate zelquistinel is ...

Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia. How this happens remains largely ...

Johns Hopkins scientists reveal that “inactive” GluD brain proteins regulate neuronal communication and open up new ...