蛋白偶联受体(GPCR)是一类在动物细胞中广泛存在的跨膜蛋白,也是哺乳动物中最大的膜蛋白家族。在我们体内,超过800种GPCR通过激活一系列信号通路影响着细胞行为,并调控多种生理功能。这类分布广泛的重要蛋白早已成为药物开发的热门靶点。据统计,超过30 ...
Infectious diseases are illnesses caused by pathogenic microorganisms—including viruses, bacteria, fungi, and parasites—that invade a host, replicate, and ...
提起GPCR,很多人或许觉得陌生,但它与人类健康的关联远比想象中紧密。作为人体内最大的一类膜受体,GPCR数量超过800种,几乎参与了所有生理过程——如果把临床医学比作一棵枝繁叶茂的大树,GPCR就是支撑整棵树的主干,既连接着基础生命过程,又支撑着现代医学的各个分支。更关键的是,约三分之一的临床药物都通过GPCR发挥作用,它无疑是药物开发的“宝藏”。
Domain Therapeutics Rebrands as Kainova Therapeutics Advancing Its Clinical Pipeline of GPCR-Modulating Therapies -- Kainova Therapeutics rebrand reflects expanding capabilities powering next stage of ...
Taste, pain, or response to stress -- nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers have uncovered the ...
A GPS-like technique has been used to track G protein-coupled receptor movement, revealing how these essential receptors function. Although G protein-coupled receptors (GPCRs) are crucial to the ...
A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled ...
Austin, Texas, Jan. 05, 2026 (GLOBE NEWSWIRE) -- G-Protein Coupled Receptors (GPCRs) Market Size & Growth Analysis: According to SNS Insider, The G-protein coupled receptors (GPCRs) market size was ...
Most protein-targeting drugs are prizes that drug developers have unearthed from G protein–coupled receptor (GPCR) interactomes. So, when GPCR-targeting drugs become harder to find, one might liken ...