Genetic variation in livestock is a critical area of research that underpins modern breeding practices and agricultural productivity. Differences in DNA sequences, including single nucleotide ...

The nematode Caenorhabditis elegans serves as a preeminent model for understanding the intricate relationship between genetic variation and phenotype. Recent advances have harnessed high-throughput ...

Engineers at the University of California have developed a new data structure and compression technique that enables the ...

PanMAN data structures compress pangenomes massively, encode evolutionary histories, and enable scalable analysis of millions of genomes.

Researchers have significantly expanded the catalogue of known human genetic variation. The resulting datasets, shared in two back-to-back publications in the journal Nature, constitute what may be ...

This important study, which tackles the challenge of analyzing genome integrity and instability in unicellular pathogens by introducing a novel single-cell genomics approach, presents compelling ...

A research team led by Zhiping Weng, Ph.D., and Jill Moore, Ph.D."18, at UMass Chan Medical School, has nearly tripled the ...

Pangenomics studies generate huge amounts of data. A new data compression method could make pangenomic analysis accessible to ...

Sequencing nearly half a million genomes, researchers show that most additive genetic influences on height, lipids, and other complex traits are now directly measurable, while pinpointing ultra-rare ...

Structural variations (SVs), including insertions, deletions, inversions, and substitutions, can profoundly influence gene regulation and phenotype. In plants, these variants are particularly ...

Learn about the woolly rhino genome that was recovered from a wolf's stomach, providing insight on the extinct species' genetic health.