The human liver plays a pivotal role in drug metabolism, largely attributable to the diverse family of UDP-glucuronosyltransferases (UGTs) that catalyse glucuronidation reactions. This conjugation ...

Researchers are developing functional, patient-specific livers using 3D bioprinting and stem cell technology to eliminate the ...

The majority of human illnesses is caused by damage of a single organ like the liver whose failure accounts for 2M deaths worldwide every year. Orthotopic transplants are the only curative therapy ...

Differentiated hepatocyte organoids formed networks of small canals that allowed bile acid to pass, in a manner similar to human tissue. While organoids aim to mimic human organs, the liver’s ...

Patients with severe liver disease could one day be kept alive with livers transplanted from pigs, scientists say. A team in China successfully transplanted the liver from a miniature pig that had ...

Long before a liver tumor appears, a high-fat diet can push liver cells into a risky survival mode. That is the central ...

A genetically modified porcine liver has been successfully transplanted into a human subject, constituting a historic precedent in the field of organ transplantation. The liver demonstrated functional ...

An important new study in the Journal of Hepatology, published by Elsevier, reports the world's first auxiliary liver xenotransplant from a genetically engineered pig to a living human recipient. The ...

A team of researchers led by bioengineer Shaochen Chen will use 3D printing techniques to shape stem cells produced by local firm Allele Biotechnology ...

A multidisciplinary team from China has successfully transplanted a gene-modified pig liver into a human recipient diagnosed with brain death. During a 10-day observation period, the porcine liver ...