本研究聚焦于急性胰腺炎（AP）的发病机制，针对胰岛素样生长因子-1（IGF-1）的保护作用展开深入探索。研究人员通过构建雨蛙素诱导的小鼠AP模型，结合β-arrestin1基因敲除（KO）动物及IGF-1R抑制剂PPP、NF-κB抑制剂Bay11708和STAT3抑制剂S3I-201等干预手段，系统阐明了 ...

Since its discovery over 50 years ago, the biological aspects of insulin-like growth factor-1 (IGF-1) have been determined to be extensive. Ranging from cell proliferation, cell differentiation and ...