Representative cryo-electron microscopy image: a coloured image of the 3D structure of gephyrin, which was calculated from the data. A team of scientists from the University of Cologne’s Institute of ...

The way the brain develops can shape us throughout our lives, so neuroscientists are intensely curious about how it happens.

Balanced synaptic inhibition, controlled by multiple synaptic adhesion proteins, is critical for proper brain function. MDGA1 (meprin, A-5 protein, and receptor protein-tyrosine phosphatase mu [MAM] ...

Whether picking up a small object like a pen or coordinating different body parts, the cerebellum in the brain performs essential functions for controlling our movement. Researchers investigated how a ...

The latticework of extracellular protein that surrounds brain cells forms a particularly dense mesh around fast-spiking interneurons. Why do these cells need such thick coats? In the July 17 Nature ...

New research reveals how a class of neurons that help coordinate communication in the brain link up with their target cells, identifying two molecules that must be present before synapses, the ...

Researchers identify two key proteins that allow chandelier cells to connect with excitatory neurons. This "handshake" regulates brain signals and, when disrupted, may lead to epilepsy or autism.

A researcher has developed a new model that provides a holistic view on how our brain manages to learn quickly and forms stable, long-lasting memories. Their study sheds light on the crucial role of ...

What are the three modes of neurotransmission, and how do they differ in terms of temporal coupling with action potentials? There are three modes of neurotransmission: stimulation-dependent release ...