The research demonstrates that increased matrix stiffness activates the protein MRTF-A, which suppresses glycolysis in NPCs. The study employs advanced techniques, including RNA sequencing and gas ...

A new study, led by Prof. Liu from the department of pharmacy, University of Electronic Science and Technology of China, discovered that the extracellular cell matrix (ECM) could induce the drug ...

Schematic diagram depicting the mechanism of the rigid matrix regulating cell glycolysis in degenerated NPCs. In degenerated NP tissue, MRTF-A was activated by increased matrix stiffness and ...