Mendelian randomization is not affected by the confounding inherent in observational studies but it does rely on several assumptions, which can be hard to test Mendelian randomization can provide a ...

Global and genetic analyses link low physical activity to rising heart disease mortality, while higher activity levels appear ...

Mendelian randomization is a study design that uses genetic variants as instrumental variables to test the causal effect of a (non-genetic) risk factor on a disease or health-related outcome. Since ...

Higher BMI and IBD causally increase hidradenitis suppurativa risk, large study finds, providing actionable insights for ...

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