Having a pill that alleviates chronic pain without adverse side effects or the risk of addiction remains an unmet pharmaceutical need for millions of people currently using traditional opioid drugs.
Fentanyl, a mu-opioid receptor agonist, is one of the most commonly used analgesics in hospitals, and may induce long-lasting behavioral and somatosensory impairment in rodents. However, whether the ...
Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid (pronounced "mew-opioid") receptors. What they didn't know - until now - was ...
Morning Overview on MSN
Scientists watch drug molecules hit cell receptors in real time
Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...
University of Florida scientists have helped identify a novel drug compound that selectively activates pain-altering receptors in the body, offering a potentially safer alternative to conventional ...
University of Florida scientists have helped identify a novel drug compound that selectively activates pain-altering receptors in the body, offering a potentially safer alternative to conventional ...
Morning Overview on MSN
Scientists design opioids that ease pain with fewer dangers
Scientists are racing to redesign how powerful painkillers work, aiming to keep the relief that opioids provide while stripping away the worst dangers of addiction and overdose. Instead of tweaking ...
University of Florida scientists have helped identify a novel drug compound that selectively activates pain-altering receptors in the body, offering a potentially safer alternative to conventional ...
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