"Until meningitis is ruled out through lumbar puncture, septic very-low-birth-weight infants at high risk of mortality should receive empiric antimicrobials with high delivery through the blood-brain ...

Neonatal sepsis remains a critical condition in intensive care, characterised by a systemic infection that can lead to rapid clinical deterioration in newborns. Early identification is vital, and ...

Early-onset neonatal bacterial infection is a major cause of morbidity and mortality, especially in preterm newborns. It is most often caused by ascending infection via the maternal genital tract.

A genetic signature in newborns can predict neonatal sepsis before symptoms even start to show, according to a new study. The study, led by University of British Columbia and Simon Fraser University ...

Sepsis leads to life-threatening organ failure due to dysregulated host responses to infection and presents uniquely across age groups. Neonatal sepsis, affecting infants in their first 28 days, ...

An international clinical trial co-led by UCL (University College London) researchers will evaluate much-needed new antibiotic combinations for newborn babies with sepsis. The trial, which has started ...

Low-cost infection prevention and control measures present a valuable opportunity to mitigate the spread of Klebsiella pneumoniae, according to a new study led by researchers at Boston University ...

LISBON, Portugal — A shift toward broader-spectrum antibiotics and increasing antibiotic resistance has led to high levels of mortality and neurodevelopmental impacts in surviving babies, according to ...