Yes, as the Exchange 2010 extensions are executed on the server side, you're just connecting to that remote powershell instance from your local powershell client. It is possible to run Exchange Server ...

See subject. Exchange 2013. 4 node DAG, all roles have CAS/MBX on them and local storage. Kemp load balancer in front of all of it. When I open the Exchange Management Shell (powershell) on a server, ...