Osteoporosis is a common skeletal disorder characterized by excessive bone loss, leading to increased fragility and an increased risk of fractures. Osteoclasts, the bone-resorbing cells, are widely ...

Researchers led by Kanazawa University show that messages sent by osteoblasts via extracellular vesicles trigger the formation of mature osteoclasts during fracture healing Kanazawa, Japan - In a ...

The skeleton undergoes continuous remodeling throughout life in response to diverse environmental stimuli. Osteoclasts, which are specialized cells on the bone surface, break down old bone tissue (in ...

Imaging technology shows that bone-resorbing osteoclasts gather in distinct pockets, leading to new insights for osteoporosis and cancer treatment. Cutting-edge imaging sheds new light on cells that ...

Researchers at the Garvan Institute of Medical Research have discovered a new type of bone cell that may reveal new therapeutic approaches for osteoporosis and other skeletal diseases. The new cells, ...

Bone-dissolving cells called osteoclasts are derived from a type of immune cells called macrophages. They are necessary for the maintenance and renewal of bones. But the intracellular mechanisms ...

As part of our natural bone development, special cells on the surface break down old bone tissue and then build it back up again. When changes occur to this cycle and throw things off balance, ...

Researchers at the Garvan Institute of Medical Research have discovered a new type of bone cell that may yield novel therapeutic targets and strategies for osteoporosis and other skeletal diseases.

A new discovery about osteoporosis suggests a potential treatment target for that brittle-bone disease and for bone loss from rheumatoid arthritis. The findings from University of Virginia School of ...

An existing drug that targets senescent, or sleeping cells could provide the answer to treating lower back pain, according to a new study. An existing drug that targets senescent, or sleeping cells ...