Considerable advances have been made in the understanding of the pathogenesis and treatment of secondary hyperparathyroidism (SHPT) in chronic kidney disease (CKD). These include the discovery that ...

Deletion of the ‘glial cells missing-2’ gene in mice disrupts development of the parathyroid glands but does not eliminate production of parathyroid hormone (PTH), which is required for calcium ...

The parathyroid glands are four small glands located in the neck. They regulate the amount of calcium in the blood. If the glands are over-functioning, an individual may need surgery to remove one or ...

Patient-derived parathyroid organoids (PTOs) could pave the way for future physiology studies and drug-screening applications, as shown in a study published on October 27 in the journal Stem Cell ...

The endocrine system comprises glands and tissues that produce hormones to regulate and coordinate vital bodily functions. This article, the third in an eight-part series on the endocrine system, ...

An investigational drug, encaleret, restored calcium levels in people with autosomal dominant hypocalcemia type 1 (ADH1), a rare genetic disorder marked by an imbalance of calcium in the blood and ...

However, despite suggestions that such secondarily stimulated hyperparathyroidism may become autonomous 12–14 convincing data regarding such a possibility are not available, owing to the great excess ...

Dawn Ethier, a police officer in Ottawa, Canada, recalls how her life revolved around managing her 100-pill-a-day regimen. Her symptoms began 3 weeks after her thyroid surgery, but it took another 4 ...

Exposure to radiation may result in late adverse effects. Here we describe the consequences of irradiation for the endocrine system, particularly the parathyroid glands, in a cohort of 61 “liquidators ...