Inherited platelet disorders represent a heterogeneous group of genetic conditions that affect the number, size, or function of platelets, with clinical manifestations ranging from mild mucocutaneous ...

Abstract and Introduction Review of Normal Platelet Physiology and Megakaryocytopoisis Qualitative Platelet Abnormalities Conclusion References Nitric oxide (NO) is another drug used in the neonatal ...

The 2025 American Society of Hematology (ASH) meeting in December presented a clear message: scientific innovation and ...

Thrombocytopenic disorders include numerous causes of decreased platelet production or increased platelet destruction. Having too few platelets can lead to internal or serious bleeding after surgery ...

Since the discovery of platelets approximately 160 years ago, extensive research has characterized how platelets function and clarified their role in hemostasis, thrombosis, and in a number of ...

Monocytes, a special type of white blood cell, secrete cytokines as inflammatory messengers that are crucial for an appropriate immune response. Researchers at the University Hospital Bonn (UKB) and ...

A new miniature 3D model of human bone marrow has just been described. The model may help clinicians predict which patients will benefit from a new therapy for blood platelet disorders, such as ...

Even as biomedical engineer Anirban Sen Gupta refines artificial platelets to stem traumatic bleeding, he and his colleagues are seeking new uses for their synthetic solution. The latest application ...

Biomedical engineers report a new application for their synthetic platelets: treating the genetic condition that prevents blood from clotting, Von Willebrand disease (VWD). The most common of all ...

Megakaryocytes, which are derived from hematopoietic stem cell precursors in bone marrow, form and release platelets; these circulate in the blood for 8 to 10 days before they are removed by hepatic ...