Potassium channels are essential membrane proteins that enable the selective and rapid transport of K⁺ ions, a process fundamental to cellular excitability and signal transduction. Recent research has ...

ATP-sensitive potassium (KATP) channels are critical molecular sensors that link cellular metabolism with membrane excitability. Composed of inward rectifier potassium channel subunits coupled to ...

A key approach to understanding the brain is to observe the behavioral effects of turning on specific populations of neurons. One of the most popular approaches to controlling neuronal activity in ...

Lysosomes require tight regulation of their pH to degrade their contents. Researchers know that V-ATPase pumps protons into these little digestive sacs, but what protein shuttles the ions back out?

A new study has unveiled a precise picture of how an ion channel found in most mammalian cells regulates its own function with a 'ball-and-chain' channel-plugging mechanism. The findings boost the ...

Researchers decipher the function of an ion channel involved in cellular degradation processes and create new possibilities for Parkinson's ...

Molecular Devices, at SLAS 2015, launched a homogeneous, no-wash assay to measure ligand- and voltage-gated potassium channel activity. The FLIPR® Potassium Assay Kit uses a novel thallium-sensitive ...