A new study reveals a critical vulnerability in a brain receptor targeted by a rare autoimmune disease. Researchers have ...

Histamine is widely known for its role in allergic reactions but also functions as a key neurotransmitter in the brain, where ...

When a highly pathogenic strain of H5N1 influenza virus emerged in US dairy cattle in March, scientists around the world had a slew of questions about the virus’s characteristics. In a new paper ...

The ability to grow stem cell-derived biological tissues, such as skin and other organs, in the laboratory holds promise for applications in areas including wound healing and transplants. However, ...

A new study found that a single mutation to the hemagglutinin protein of an H5N1 virus isolated from a dairy worker in Texas this spring switched the protein’s binding specificity from avian- to human ...

A new editorial paper was published in Oncoscience, titled "PH-binding motifs as a platform for drug design: Lessons from protease-activated receptors; PARs." While targeted cancer therapy is greatly ...

Researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, in collaboration with Osaka University and ...

Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...

Scientists are aiming to determine the composition and topology of physiological Ashwell-Morell receptor ligands. Their findings will help uncover the receptor's still-hidden secrets. After earning ...

Of the 20,000+ human genes, none has greater influence on late-onset Alzheimer’s disease than APOE. But why do certain variants of this lipid transporter protect the brain, while others endanger it? A ...