Asymptotically, sample proportions from a multinomial distribution converge in distribution to a multivariate normal distribution with a singular negative product correlation structure. Based on this ...

Correlated samples have been frequently avoided in case-controlgenetic association studies in part because the methods for handling them are either noteasily implemented or not widely known.

Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations—CONCORDE BayeSize applies the concept of effect size ...