A new study adds to evidence which suggests treating breast cancer patients with sodium channel blockers could be a promising future treatment to prevent the spread of cancer during the gap between ...

In work that spans molecular to cognitive aspects of Alzheimer's disease, scientists have shown that one of the changes in the brains of mice with Alzheimer's is a reduction in certain types of ...

Blockade of voltage-gated sodium channels (NaChs) in pancreatic α cells has anti-diabetic effects, according to research published online May 8 in Diabetes. Arvinder K. Dhalla, Ph.D., of Gilead ...

A new study on live tissue cells is the first to reveal how channels that allow sodium to enter into breast cancer cells enable tumours to grow and spread. The discovery adds to evidence which ...

Nat Clin Pract Neurol. 2008;4(3):159-169. Drug Primary clinical use Protective effect during administration in animal models? Effects of withdrawal in EAE Clinical study Phenytoin Treatment of ...

South Korea’s SK Biopharmaceuticals Co. Ltd. and Shanghai-based Ignis Therapeutic Co. Ltd. signed a ₩804 billion (US$58 million) licensing deal on April 18, granting the latter global rights to a ...

WATERTOWN, Mass.--(BUSINESS WIRE)--Nocion Therapeutics, Inc., a clinical stage biopharmaceutical company developing novel small molecule charged sodium channel blockers called “nocions”, that ...

PHILADELPHIA -- An oral, non-addictive sodium channel blocker safely relieved moderate-to-severe acute pain following surgery, according to phase III data that could support regulatory approval.

Little additional work has been performed beyond that of Lee et al. [1,3,10] to further investigate the proposed dual action of ibutilide. Our laboratory has sought to examine the effects of sodium ...

This issue highlights drug-delivery strategies and technologies, from nanoscale delivery systems to implantable biomaterial drug depots to microneedle arrays, for a number of biomedical applications ...