Spasticity is involuntary overactivity of muscles that occurs following upper motor neuron damage to the brain or spinal cord. Upper limb spasticity is common after stroke and can cause deformity, ...

Spinal cord injury (SCI) causes paralysis in roughly one million people worldwide, with incident cases rising yearly. Beyond motor and sensory deficits, patients frequently experience muscle atrophy, ...

Botulinum toxin type A was first used for the treatment of spasticity in 1989. A small uncontrolled study of treatment of upper limb spasticity after stroke reported encouraging benefits, including ...

Spasticity most often develops in upper motor neuron types of injuries. It is a motor disorder defined as velocity dependent, increased resistance to passive muscle stretch. It is an exaggeration of ...

Arbaclofen extended-release (ER) reduced spasticity in patients with multiple sclerosis and was found to be safe and well-tolerated, according to 2 new abstracts presented at the 33rd Annual Meeting ...

Investigators sought to determine the safety and efficacy of twice-daily dosing of arbaclofen ER in patients with spasticity due to multiple sclerosis. SEATTLE – Twice-daily arbaclofen ...