系统性硬化症（Systemic sclerosis，SSc），常被称为“硬皮病”，是一种罕见的慢性自身免疫性疾病。它远非简单的皮肤病变，而是以免疫系统紊乱、微血管病变及多器官进行性纤维化为特征，被称为“人体内的水泥病”。 患者皮肤逐渐硬化、紧绷，关节活动受限，更严重的是，肺、心脏、消化道等内脏器官也会因异常纤维化而功能受损，威胁生命。 全球数据显示，该病患病率约为每百万人口50-300例，且女性发 ...

Mycophenolate mofetil treatment in patients with limited cutaneous systemic sclerosis is linked to a reduced need for escalation of vasoactive or vasodilator therapies for vascular complications.

Systemic sclerosis causes the skin to tighten and harden resulting in a potentially fatal autoimmune condition that is associated with lung fibrosis and kidney disease. University of Michigan Health ...

The VEDOSS project has previously shown that 70% of patients with Raynaud's phenomenon and at least one red flag – systemic sclerosis (SSc)-specific antibodies, puffy fingers, or an SSc pattern on ...

Scleroderma on the face can cause symptoms that may affect your appearance, including the texture, discoloration, and elasticity of your skin. Medications, facial exercises, and dermatological ...

AMSTERDAM — For patients with diffuse cutaneous systemic sclerosis, an autoimmune disease for which there are few treatment options, lenabasum (JBT-101, Corbus Pharmaceuticals) shows potential, new ...

"Single-pathway inhibition has demonstrated modest effects in rheumatic diseases like SSc. This is why we believe tibulizumab's dual-pathway approach holds the potential to be best-in-class, aiming to ...

As Bob Saget is remembered by his friends and co-stars, one memory that stands out is his commitment to finding a cure for scleroderma, a rare disease for which Saget was the most high-profile ...

Mediar Therapeutics, Inc., a clinical-stage biotechnology company advancing first-in-class therapies designed to halt ...