The anti-tumor immune response involves a series of complex steps mediated by various immune cells and signaling molecules.

Higher levels of CD4-positive naïve T cells in patients receiving CAR T-cell therapy for multiple myeloma are associated with ...

Data presented at ASH 2025 suggest earlier-line use of cilta-cel leads to better outcomes in multiple myeloma because patients have fitter immune systems and less exhausted T cells, improving CAR T ...

The Golgi apparatus modifies, sorts and packages proteins to be sent to their final destinations, whether that's within or outside of the cell. It's a core function, but little studied in the setting ...

CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...

Researchers investigating ways to reduce exhaustion in cancer-fighting T-cells found that the Golgi apparatus can be used as a simple marker -- more Golgi means a more robust cell. The Golgi apparatus ...

An engineered viral protein enhanced the anticancer function of T cells in mice, suggesting a new strategy to improve immunotherapy. Courtney and his team sought to exploit this property of TIP to ...