An important goal in drug development is to engineer inhibitors and ligands that have high binding affinities for their target molecules. In optimizing these interactions, the precise determination of ...

A common method of quantifying the presence of an analyte in a sample is through titration, remaining relevant for centuries thanks to the simplicity and accuracy of the technique. However, there is ...

Titration plays an important role in pharmaceutical analysis. Despite the recent attention given to chromatographic methods, several applications are only feasible by titration, making it a ...

A range of production processes frequently employ acid mixtures comprised of two or three acids; for example, nitric acids, sulfuric acids and hydrochloric acids. In order to use these acids safely ...

The authors developed a robust, automated system to conduct Karl Fischer moisture assays for lyophilized products. Karl Fischer titration is one of the few assay techniques recognized by the US Food ...