Figure 1: Induction of filamentous tau pathology in ALZ17 mice injected with brain extract from mice transgenic for human P301S tau. Figure 2: Temporal increase in the number of Gallyas-Braak-positive ...
Genetically engineered monkeys carrying a foreign gene that is passed on to their offspring provide a potentially valuable bridge between mouse models of disease and treatment for human disorders.
During the transformation process that creates the GMO, the transgenic construct tends to undergo deletions, duplications, and rearrangements, integrating at unpredictable sites in the host cell ...
Transgene instability has been known at least since 1994 [1] (reviewed in Genetic Engineering Dream or Nightmare, p.140), though it is seldom, if ever, reported in the popular media. Transgenes (the ...