Chronic kidney disease (CKD) is a progressive condition marked by declining renal function, which predisposes patients to systemic metabolic imbalances. A prominent complication in CKD is vascular ...

Vascular calcification, low bone mass and fragility fractures are all frequent age-dependent disorders. Recent clinical and experimental data suggest that vascular calcification and bone loss could ...

Figure 12. Schematic illustration of mechanisms involved in the protective effects of fisetin during VSMC calcification. Mineral stress with disturbed phosphate and calcium homeostasis may trigger ...

Appropriate imaging can help identify patients who need intensive medical treatment. Calcification in the cardiac valves and aorta portends worse survival and progresses faster in patients with ...

Promising therapies still need to be further evaluated in clinical trials. The first systematic review of trials of possible therapies to slow vascular calcification in chronic kidney disease (CKD) ...

Logistic regression is the most cost-effective model for medial vascular calcification classification, with a mean ICER of $278 using five low-cost features. Despite similar diagnostic accuracy, ...

Please provide your email address to receive an email when new articles are posted on . In the course of 18 months, supplementation with cholecalciferol did not attenuate vascular calcification ...

A new research paper was published in Aging (Aging-US) Volume 17, Issue 4, on April 2, 2025, titled "Fisetin ameliorates vascular smooth muscle cell calcification via DUSP1-dependent p38 MAPK ...

DUBLIN – Sanifit Therapeutics SA has found a taker for its phase III calcification inhibitor for kidney dialysis patients, SNF-472, in the shape of Vifor Pharma AG, which is acquiring the Spanish ...

A drug candidate, previously successful at treating severe fatty liver disease, reduces atherosclerosis - a primary driver of cardiovascular death worldwide - in large mammals, a study suggests.

Just as cleaning our house or any other important location is a part of good health, cleaning our arteries is also a crucial aspect of good health, but it is often overlooked. Healthy arteries ensure ...