This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).

密码子使用偏倚——某些同义密码子的优先使用——是所有基因组的一个基本特征。密码子的使用在决定基因表达水平的所有生物体中起着关键作用，迄今为止已被研究过。几乎所有感染人类的病毒都显示出与人类基因不同的密码子使用模式，但它们在宿主细胞中有效地表达它们的蛋 ...

In a recent article published in the journal Nature, researchers used a classical concept in computational linguistics to design a new algorithm, LinearDesign, which optimized the structural stability ...

Sara Moniuszko is a health and lifestyle reporter at CBSNews.com. Previously, she wrote for USA Today, where she was selected to help launch the newspaper's wellness vertical. She now covers breaking ...

Adding a photocopier gene to mRNA vaccines could make them last longer and curb side effects. This article first appeared in The Checkup, MIT Technology Review's weekly biotech newsletter. To receive ...

mRNA vaccines tell the body how to make a protein that produces immunity against specific microbes. In contrast, traditional vaccines use weakened or dead microbes, or pieces of them, to stimulate ...

In a Phase 3 trial of more than 18,000 volunteers across three countries, an mRNA influenza vaccine from Pfizer has outperformed standard seasonal flu shots by 34.5%. It's yet another sign that this ...

The most frequently used mpox vaccine provides partial immunity to the disease but isn't always able to prevent severe symptoms or disease transmission. A new vaccine candidate from Moderna, mRNA-1769 ...

mRNA vaccines helped us through the covid-19 pandemic—but they could also help defend against many other infectious diseases, offer universal protection against flu, and even treat cancer. Cast your ...

The U.S. Department of Health and Human Services (HHS) recently announced it will wind down funding for mRNA vaccine development—which could prove to be one of the costliest, deadliest decisions HHS ...

The mRNA COVID-19 vaccines might make some cancer treatments more effective. Lung cancer patients who received the vaccine within a few months of immunotherapy, which revs up the immune system, lived ...