Chemoradiotherapy in the Management of Locally Advanced Pancreatic Carcinoma: A Qualitative Systematic Review The serine-threonine kinase mammalian target of rapamycin (mTOR) plays a major role in the ...

CePA exerts a liver-targeted mTOR repressive function, alleviating MASH progression and fat accumulation in high-fat diet-fed mice. Metabolic dysfunction-associated steatohepatitis (MASH) is one of ...

As the aging population increases, the race to unpack the molecular understanding of aging heats up. The rapamycin (mTOR) complex 1 (mTORC1) is known to be a key component of multiple functions of the ...

The FDA has accepted a New Drug Application (NDA) for Celcuity’s gedatolisib in hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2), PIK3CA wild-type advanced ...