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研究发育过程中心脏缺陷的遗 传原因十分困难。本研究描述了如何利用干细胞衍生的心脏类器官来探索心脏发育早期阶段的基因表达，从而识别可能与先天性心脏病相关的基因。这项研究将发育基因调控与疾病遗传学联系起来，为深入了解先天性疾病的机制 ...

唐氏综合征（DS）由21三体综合征（TS21）引起，是导致智力障碍的最常见遗传病因(1,2)。DS的神经系统影响首先在产前发育阶段显现，表现为放射状胶质细胞（RG）神经干细胞增殖减少、皮质体积缩小以及皮质细胞类型失衡(3-6)。然而，DS中皮质神经发生改变的发育 ...

与哺乳动物不同，鸟类能够再生内耳毛细胞，修复听力损伤。为了将鸟类修复听力的机制应用于人类，比较鸟类和哺乳动物内耳毛细胞的叫声将有助于我们找到修复人类听力损伤的方法。 科学摘要： 内耳感觉毛细胞对听觉和前庭功能至关重要。在哺乳动物中 ...

CIRM funds stem cell research to institutions throughout California. On the map below, click on any marker to learn more about our funding to that institution. You can explore the awards they’ve ...

Welcome to the frequently asked questions (FAQs) page of the California Institute for Regenerative Medicine (CIRM). Here, you’ll find answers to the most common questions you may have on CIRM. CIRM, ...

When most people think about about stem cells treating disease they think of a stem cell transplant. In a stem cell transplant, stem cells are first specialized into the necessary adult cell type.

CIRM provides funding across all stages of research, from basic science to translational studies and clinical trials. This support drives best-in-class research aimed at developing innovative ...

The following information will help you comply with CIRM regulations and find information about our forms and policies. If you have questions that aren’t addressed on this page contact your Grants ...

CIRM’s Education and Training programs are a vital link to tomorrow. The California Institute for Regenerative Medicine (CIRM) offers invaluable educational and training pathways in regenerative ...

At the California Institute for Regenerative Medicine (CIRM), we are committed to the continued funding of groundbreaking research in regenerative medicine. To reflect this commitment, we are ...

CIRM is dedicated to bringing regenerative medicine treatments to patients who need them. This commitment begins with access to information. This page provides resources to learn more about ...