Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

The Trump administration is ending the use of abortion-derived fetal tissue in research funded by the National Institutes of ...

Researchers at The University of Tokyo developed TECHNO, a two-step genome editing strategy that replaces entire mouse loci with human genomic DNA. The method integrates fragments over 200 kbp.

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

Discover the innovative TECHNO platform for full-length gene humanisation, enhancing models for human gene function.

Background IBD is characterised by recurrent flares, but evidence on whether modifiable dietary factors influence flare risk ...

Pulmonary alveolar proteinosis (PAP) is a rare respiratory disease that affects somewhere between 4 and 40 people per million worldwide. The condition causes substances such as fats and proteins to ...