Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.

Researchers are investigating the role of non-coding DNA, or junk DNA, in regulating astrocytes, brain cells involved in Alzheimer's disease.

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

Only around two percent of the human genome codes for proteins, and while those proteins carry out many important functions of the cell, the rest of the genome cannot be ignored. However, for decades ...

Researchers discover a unique genetic code in Antarctic archaea that encodes a rare amino acid, potentially advancing protein engineering.

In a recent preprint* uploaded to the bioRxiv server, researchers developed and trained a foundational model to predict tissue-specific RNA expression, splicing, RNA binding protein specificity, and ...

Scientists have uncovered a rare genetic cause of intellectual disability in a historically overlooked part of the human genome: so-called junk DNA. This knowledge could someday help to diagnose some ...