- Proprietary tissue-targeted complement platform and best-in-class IL-7R antibody technology to treat patients with severe autoimmune and inflammatory disease; clinical trials begin in 2020 ...

Researchers have discovered that SARS-CoV-2 hijacks three important host proteins that dampen the activity of the complement system, a key component of early antiviral immunity. This significantly ...

Figure 1: Mannose-binding lectin (blue strands) can bind to sites on the SARS-Cov-2 spike protein on the cell membrane. One of the most striking features of the SARS-CoV-2 pandemic is that across all ...

This is a preview. Log in through your library . Abstract Rabbits sensitized by multiple injections of living BCG until their serums showed high concentrations of antibodies to tuberculoprotein and ...

Abstract: Liver-derived and serum-circulating complement is undeniably quintessential for innate immunity by detecting and eliminating infectious microorganisms. However, unexpectedly, cell-autonomous ...

Researchers at the Medical University of Vienna and the Medical University of Innsbruck discovered that SARS-CoV-2 hijacks three important host proteins that dampen the activity of the complement ...