Complex digital representations of organs were reconstructed by computationally generating virtual slices from sparsely sampled planar spatial transcriptomic data, exemplified by a 38-million-cell ...

Doudna and colleagues discuss recent advances in the targeted delivery of genome editors in vivo, offering a framework for the rational design of delivery systems. Comprehensively resolving the cell ...

Evidence from multiple model systems supports a shift away from heme transport and toward metabolic dysfunction and oxidative stress as key drivers of TANGO2 deficiency.