Purpose: Fanconi anemia is a genetically heterogeneous chromosomal breakage disorder exhibiting a high degree of clinical variability. Clinical diagnoses are confirmed by testing patient cells for ...

Figure 1: FANCB is a member of the core complex required for monoubiquitination of FANCD2. Figure 2: Nuclear localization of FAAP95 depends on FANCA. Figure 3: Evidence of a genetic defect in FAAP95 ...