This is an important study on the sensory roles of Cerebrospinal fluid-contacting neurons (CBF-cn) in mammals. The authors identify PKD2L1 as the predominant pH-sensing channel CBF-cn and show how the ...

Day to day, it might be tempting to take plants for granted. But you'd do so at your peril; our leafy brethren are staggeringly complex, as revealed when they're put under the microscope. To give ...

The identification of promising lead compounds from high-throughput screens is still a very complex problem. A new high-throughput assay for identifying aggregation-based false positives could help.