One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature. A research group has demonstrated that overexpression of ...

CDT1 inhibits the helicase activity of the MCM complex, thereby suppressing nascent strand synthesis in DNA replication in cultured human cells. This action results in fork collapse and DNA damage, ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

The world's oldest DNA comes from a 2.4 million-year-old ecosystem in Greenland. Will scientists eventually sequence even older DNA? When you purchase through links on our site, we may earn an ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. A comprehensive understanding of the atomic level mechanism governing the binding ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

Leading Manchester United’s academy is no ordinary backroom role. The club’s heritage of developing young talent is unparalleled in English football, so whoever is tasked with running it has ...

Ensuring that DNA replication occurs at the right stage of the cell cycle is of crucial importance in biology. In bacteria, DNA replication begins with the assembly of a DNA-protein complex called the ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

This valuable descriptive manuscript builds on prior research showing that the elimination of Origin Recognition Complex (ORC) subunits does not halt DNA replication. The authors obtain solid data ...

If you love creative paracord projects, mind-blowing weaves, and unique survival gear, you need to follow me! Join the Weavers of Eternity community for expert tutorials, fun challenges, and must-know ...