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细胞毒性评估方法差异如何影响微核试验结果:基于MicroFlow与镜检法 ...
为解决体外微核试验中高灵敏度流式细胞术与传统镜检法结果不一致的难题,德国联邦风险评估研究所团队以苦参碱为模型化合物,系统比较MicroFlow法和镜检法在V79细胞中的检测差异。研究发现MicroFlow法在相对生存率指标下显示苦参碱具有统计学显著的微核诱导 ...
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