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AbMole丨MSA-2:非核苷酸类STING激动剂,重塑肿瘤免疫微环境
MSA-2(AbMole,M10459)是一种非核苷酸类STING(干扰素基因刺激因子)激动剂,通过激活先天免疫通路发挥研究作用。MSA-2在溶液中以单体-二聚体动态平衡存在,但仅二聚体形式能与STING蛋白结合并触发下游信号传导,诱导干扰素-β(I ...
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